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In this course, Dr David Kennedy discusses caffeine from a research and real-world perspective. Caffeine, when taken alone in a research context, is associated with consistent ergogenic and psychological benefits, although within differing optimal dose ranges. In a real-world sport/exercise context, caffeine is often consumed alongside other bioactive compounds in the form of manufactured energy drinks or naturally occurring, plant-derived, caffeinated products. This SSE course explores the state of the research and where further exploration is needed.
Course Objectives
Course
Credits
Course Expiration
ACSM
1
02/06/2026
BOC
1
02/06/2026
Fatigue during high intensity sports or activities (~1-10 minutes in length) is caused by several components with strong evidence that muscle acidosis via accumulating hydrogen ions is a key performance inhibitor. To address this issue, skeletal muscle has intra and extracellular buffering mechanisms to attenuate exercise induced acidosis. Carnosine is an intracellular buffer that is key in slowing the decline of muscle pH. Carnosine has a nitrogen containing imidazole side ring which accepts or buffers hydrogen. This buffering can contribute as much as 15% of total buffering capacity. Additionally, carnosine has been shown to be a calcium/hydrogen exchanger, delivering calcium back to the sarcoplasmic reticulum and hydrogen away to the cell membrane. This suggests that carnosine may increase calcium sensitivity and muscle contraction efficiency. Plasma beta-alanine is the rate limiting substrate of carnosine. Approximately 3-6 g/d of beta-alanine supplementation over at least four weeks can elevate muscle carnosine stores by 30-60%. Several meta-analyses have been conducted and has shown 2-3% increased performance in non-elite athletes, followed with just 0.5-1% increased performance in elite athletes.
Course Objectives
Course
Credits
Course Expiration
ACSM
1
06/24/2024
BOC
1
06/23/2024
Commission on Dietetic Registration
1
06/23/2024
CSCCa
1
06/23/2024
Caffeine is one of the most studied supplements and has shown ergogenic effects in almost every sport scenario it has been studied. The benefits of ingesting moderate to high doses of caffeine (5-9 mg/kg of body mass) before and during exercise have been well established in endurance exercise. Although the moderate to high doses of caffeine improves endurance performance, side effects such as gastrointestinal upset, nervousness, mental confusion, inability to focus and disturbed sleep have been reported. Lower doses of caffeine (<3 mg/kg of body mass) have been shown to have similar performance benefits as the moderate to high doses, and without the side effects. In addition to endurance performance, caffeine also improves performance in stop-and-go and team sports that require short-term, high intensity movements. Caffeine seems to have an antagonistic interaction with adenosine receptors in the central and peripheral nervous system, which increases central drive and reduces the perception of fatigue and pain during exercise. There is some variation between individuals in response to the effects of caffeine and it is unclear whether genetic polymorphisms can explain the inter-individual seen during caffeine administration.
Course Objectives
Course
Credits
Course Expiration
ACSM
1
10/08/2023
BOC
1
10/08/2023
Commission on Dietetic Registration
1
10/08/2023
CSCCa
1
10/08/2023
The mechanism of how polyphenol supplementation affects performance is complex and not fully understood. Polyphenols are derived from fruits and vegetables and are associated with color and taste. Approximately 90% of polyphenols are not absorbed in the small intestine, thus they are subsequently made available by colon gut bacteria in the source of phenolic acids. The phenolic acids are then able to be absorbed. Beneficial effects of polyphenol supplementation may include improved endurance, repeated sprint performance, and faster recovery of muscle strength however, only a small number of studies have been conducted to date and more research is needed to understand the ergogenic potential of polyphenol supplementation.
Course Objectives
Course
Credits
Course Expiration
ACSM
1
05/26/2023
BOC
1
05/26/2023
Commission on Dietetic Registration
1
05/26/2023
CSCCa
1
05/26/2023